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SPRAVATO® is a prescription nasal spray that offers a new approach to treating certain types of depression. It is specifically designed for adults who have not found relief from at least two different antidepressant treatments. SPRAVATO® works differently from traditional antidepressants, providing an alternative for those with treatment-resistant depression.
SPRAVATO® contains esketamine nasal spray, which targets the NMDA receptor in the brain. This action helps to restore connections between brain cells and improve mood. Unlike traditional antidepressants that may take weeks to show effects, SPRAVATO® can work more quickly, often providing relief within hours to days.
Treatment with SPRAVATO® is administered under the supervision of a healthcare professional in a certified medical facility. During each session, you’ll self-administer the nasal spray while being monitored. After administration, you’ll be observed for at least two hours to monitor for any side effects.
Common side effects may include dizziness, nausea, and a sense of disconnection from reality. These effects are typically temporary and resolve shortly after the session. It’s important to arrange transportation home, as you should not drive or operate machinery until the next day.
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SPRAVATO is intended for adults with treatment-resistant depression, meaning they’ve tried at least two different antidepressant treatments without adequate relief. It’s also approved for adults with major depressive disorder experiencing suicidal thoughts or behaviors.
However, SPRAVATO® may not be suitable for individuals with certain medical conditions, such as aneurysms, uncontrolled hypertension, or a history of substance abuse. A thorough evaluation by a healthcare provider is necessary to determine eligibility.
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